Biggest issue is that there isn't a feature rich adblocker. A basic one is included, but that's it. Other than that, it takes a different mindset. For example there is no build-in password manager. You're supposed to integrate your preferred tools yourself. I like that customization aspect of it. For example opening video links directly in mpv or even downloading videos directly.

Entering text is somewhat cumbersome because of different muscle memory I have from previous browsers. You need to be in 'insert mode', just like in vim, to enter text. Or set up an external editor for that. Clicking inside a textbox brings up a cursor, but you need to press 'i' to start 'insert mode'. Clicking inside the same textbox while being in 'insert mode' takes you out of it again, which makes copy/paste a little annoying.

I'd completely move over to it, if it wasn't for heavy lifting adblocking having become a necessary, though. Last time I checked, extension support was something planned for the future. Not sure how far this has gotten. I'm on an LTS distribution that doesn't have up to date versions of qutebrowser. I meant to switch to a rolling-release one, but haven't done so, yet.